As the co-founder of the Human Immune Monitoring Shared Resource (HIMSR) at the University of Colorado School of Medicine, I ensure the generation of high quality human translational research data in immunology. The HIMSR provides expertise in high parameter immunologic assays that interrogate liquid and tissue biopsies, including multiplex tissue imaging and spatial transcriptomics. I direct an impressive team of researchers with over 53 years of experience in multiplex IHC, histology, antibody optimization, and image analysis. My personal research interests continue to be in discovering the mechanisms of immune disfunction and in establishing rationale for clinical trials that aim to improve outcomes in patients.